SM-15178

Overview

SM-15178 is a potent, orally active and selective leukotriene B 4 ( LTB 4 ) receptor antagonist with an IC 50 of 0.30 μM. SM-15178 attenuates LTB 4 ( HY-107608 )-induced neutrophil accumulation in mouse skin and bronchoconstriction in guinea pigs. SM-15178 emonstrates significant anti-inflammatory efficacy across multiple animal models of inflammation. SM-15178 can be used for the research of chronic inflammatory diseases such as inflammatory bowel disease, psoriasis, and asthma.

Application

Products | Products > Disease Areas > Psoriasis | Products > Disease Areas > Inflammatory Bowel Disease | Products > Disease Areas > Asthma | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Skin Inflammation | Products > Disease Areas > Lower Respiratory Inflammation | Products > Disease Areas > Respiratory Inflammation | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Leukotriene Receptor

Product Information

• Catalog No.: HY-180411
• CAS No.: 146461-98-5
• Molecular Formula: C22H26N2O6
• Molecular Weight: 414.46
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source