Premafloxacin is a potent antimicrobial agent that exhibits activity against Staphylococcus aureus , Corynebacterium bovis , and Corynebacterium amylocolatum . Premafloxacin demonstrated potent antimicrobial activity against S. aureus by targeting topoisomerase IV , and is a poor substrate for NorA efflux pump. Premafloxacin can be used for antimicrobial research.
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