19-Nor-22-oxa-1a,25(OH)2-VD3 is a vitamin D₃ analogue. 19-Nor-22-oxa-1a,25(OH)2-VD3 has an extremely low affinity for the vitamin D receptor ( VDR ) and hardly binds to the vitamin D binding protein (DBP). 19-Nor-22-oxa-1a,25(OH)2-VD3 can effectively induce the differentiation of HL-60 cells and cause G₀-G₁ phase cell cycle arrest. 19-Nor-22-oxa-1a,25(OH)2-VD3 can be used to study diseases such as excessive hyperparathyroidism.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Thyroid Disease | Products > Disease Areas > Hyperthyroidism | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Endocrinology | Products > Signaling Pathways > VD/VDR
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