CAB7-3

Overview

CAB7-3 is an orally active HBV capsid assembly modulator (CAM). CAB7-3 exhibits an exceptional antiviral efficacy reducing HBV DNA with an EC 50 = 70 nM, CC 50 = 32.3 μM in HepDES19 cells. CAB7-3 exhibits significant anti- HBV activity in HBV -integrated HepDES19 ( EC 50 = 70 nM), HepAD38 ( EC 50 = 1 nM) and HBV-infected HLCZ01 cells ( EC 50 = 2 nM), respectively. CAB7-3 effectively reduces Hepatic HBV core protein levels and suppresses viral replication in vivo. CAB7-3 demonstrates a favorable drug-like and safety profile. CAB7-3 can be used for Hepatitis B Virus ( HBV ) research.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Hepatitis Virus Infection | Products > Disease Areas > Hepatitis B Virus Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > HBV

Product Information

• Catalog No.: HY-180524
• CAS No.: 3014372-17-6
• Molecular Formula: C28H28BBrFN5O5S
• Molecular Weight: 656.33
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source