11β-HSD1-IN-25

Overview

11β-HSD1-IN-25 is a selective and orally active 11β-HSD1 inhibitor. 11β-HSD1-IN-25 effectively reduces glucocorticoid levels in vitro and serum, and diminishes lipid accumulation in both vitro and vivo. 11β-HSD1-IN-25 modulates lipid metabolism through dual mechanisms: inhibition of 11β-HSD1 and activation of the AMP-activated protein kinase ( AMPK ) signaling pathway. 11β-HSD1-IN-25 can be used for obesity and related metabolic disorders research.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Obesity | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > 11β-HSD | Products > Signaling Pathways > AMPK

Product Information

• Catalog No.: HY-180549
• CAS No.: 1261266-23-2
• Molecular Formula: C21H12F8O
• Molecular Weight: 432.31
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source