BVT-2733 hydrochloride is a potent, selective and orally active nonsteroidal 11β-HSD1 inhibitor. BVT-2733 hydrochloride is more potent against mouse 11β-HSD1 enzyme ( IC 50 =96 nM) than against human 11β-HSD1 enzyme ( IC 50 =3341 nM). BVT-2733 hydrochloride has the potential to be used in the study of arthritis and obesity-related diseases.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > 11β-HSD
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