Pyrimethamine

Overview

Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic–folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate.

Application

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Product Information

• Catalog No.: HY-18062
• CAS No.: 58-14-0
• Molecular Formula: C12H13ClN4
• Molecular Weight: 248.71
• Purity: 99.99%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (10.05 mM); Clear solution
• Availability: In-stock

Source

Original product source