c-Kit-IN-14 (Compound 1) is a c-kit kinase inhibitor. c-Kit-IN-14 inhibits the phosphorylation of wild-type c-kit , with an IC 50 of 0.4 nM for pKIT. c-Kit-IN-14 inhibits Exon 11 KIT , with an IC 50 of 0.4 nM. c-Kit-IN-14 can be used in the research of mast cell-mediated diseases such as urticaria.
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