CK-571 is a potent and selective inhibitor of smooth muscle myosin-2 ( SMM ), with an IC 50 value of 86 nM. CK-571 exhibits IC 50 values for cardiac muscle myosin (CMM), skeletal muscle myosin (SKM), and non-muscle myosin-2A (NMM-2A) of 2.3, 42, and 0.58 μM, respectively. CK-571 can be used for research on asthma, chronic obstructive pulmonary disease, and other smooth muscle-related diseases.
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