BCFTP

Overview

BCFTP is a potent, orally active and selective human Mas-related G protein-coupled receptor X1 ( MrgprX1 )-positive allosteric modulator. BCFTP selectively potentiates MrgprX1 signaling in HEK293 cells. BCFTP alleviates specific neuropathic pain-related behaviors in a humanized MrgprX1 mouse model of chronic constrictive injury (CCI) in a MrgprX1-dependent manner. BCFTP synergistically enhances psychoactive substances analgesia in CCI MrgprX1 mice. BCFTP can be used for neuropathic pain research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Mas-related G-protein-coupled Receptor (MRGPR)

Product Information

• Catalog No.: HY-180802
• CAS No.: 2781215-95-8
• Molecular Formula: C23H17ClF4N2O2S
• Molecular Weight: 496.90
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source