MAO-B-IN-50 (Compound C20) is a selective MAO-B inhibitor with an IC 50 value of 0.06 μM. MAO-B-IN-50 shows good inhibitory effects on the aggregation of Aβ40/42 and Tau proteins, with overall IC 50 values around 1 μM. MAO-B-IN-50 exhibits potent and selective AChE inhibition ( IC 50 = 1.78 μM). MAO-B-IN-50 can be used in the research of Alzheimer's disease.
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