Aβ/tau aggregation-IN-4

Overview

Aβ/tau aggregation-IN-4 (Compound D21) is an Aβ/tau aggregation inhibitor. Aβ/tau aggregation-IN-4 promotes the degradation of Aβ40/42 (Aβ40, IC 50 = 2.151 μM; Aβ42, IC 50 = 3.622 μM). Aβ/tau aggregation-IN-4 shows selective AChE inhibition ( IC 50 : 5.56 μM). Aβ/tau aggregation-IN-4 inhibits MAO-A and MAO-B with IC 50 s of 0.59 μM and 0.09 μM, respectively. Aβ/tau aggregation-IN-4 suppresses intracellular ROS levels. Aβ/tau aggregation-IN-4 can be used in the research of Alzheimer's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Tau Protein | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > Cholinesterase (ChE) | Products > Signaling Pathways > Monoamine Oxidase

Product Information

• Catalog No.: HY-180843
• CAS No.: 3105860-83-8
• Molecular Formula: C17H12N2O6
• Molecular Weight: 340.29
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source