Desfluoro-BMS-694153

Overview

Desfluoro-BMS-694153 (Compound 3) is a calcitonin gene-related peptide receptor ( CGRP receptor ) antagonist, with a K i value of 0.01 nM. Desfluoro-BMS-694153 has a significantly reduced risk of CYP3A4 inhibition, and its IC 50 values for CYP3A4-BFC and CYP3A4-BZR are 36 and 6 μM respectively. Desfluoro-BMS-694153 can be used for research on migraines.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Disease Areas > Chronic Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > CGRP Receptor | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-180955
• CAS No.: 773886-89-8
• Molecular Formula: C35H46N8O3
• Molecular Weight: 626.79
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source