NEP108

Overview

NEP108 is a GID4 E3 ligase-based BRD4 PROTAC degrader, with its DC 50 value approximately 3.8 μM. NEP108 has a strong affinity for GID4, with a K D value of 0.22 μM, and the K D value of its trimeric complex is 2.85 μM. NEP108 can be used for cancer research. (Pink: BRD4 ligand ( HY-78695 ); Blue: Ligands for E3 Ligase ligand ( HY-D2259 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Epigenetic Reader Domain

Product Information

• Catalog No.: HY-180957
• CAS No.: 3031840-31-7
• Molecular Formula: C47H51ClN10O4S
• Molecular Weight: 887.49
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source