PRE-084

Overview

PRE-084 is a highly selective σ1 receptor ( S1R ) agonist, with an IC 50 of 44 nM. PRE-084 exhibits good neuroprotective effects, can improve motor function and motor neuron survival in mice. PRE-084 also can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Sigma Receptor | Products > Signaling Pathways > Akt | Products > Signaling Pathways > NO Synthase

Product Information

• Catalog No.: HY-18100
• CAS No.: 138847-85-5
• Molecular Formula: C19H27NO3
• Molecular Weight: 317.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source