GSK190937

Overview

GSK190937 is a type II platelet-derived growth factor receptor alpha ( PDGFRA ) human kinase inhibitor with antimalarial activity. GSK190937 can inhibit the formation of hemozoin in the malaria parasite , resulting in the accumulation of free hemoglobin within the malaria parasite . GSK190937 shows IC 50 values of 0.22, 0.59 and 0.25 μM against P. falciparum NF54, K1 and Dd2 parasite . GSK190937 shows an IC 50 of 25 μM for CHO cells. GSK190937 can be used for research of malaria.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Plasmodium Infection | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > PDGFR | Products > Signaling Pathways > Parasite

Product Information

• Catalog No.: HY-181108
• CAS No.: 2651234-01-2
• Molecular Formula: C22H20Cl2N4O
• Molecular Weight: 427.33
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source