G194-0712

Overview

G194-0712 is a selective histone deacetylase 5 ( HDAC5 ) activator with an EC 50 of 7.96 μM and a K d of 2.53 μM. G194-0712 restores ACTN4-K417 deacetylation and nuclear import, and increases CSTA expression. G194-0712 accelerates wound closure in chronic wound models, reducing wound area and epithelial gap. G194-0712 can be used for the research of chronic skin wounds, such as diabetic wounds, ischemic wounds, radiation injury wounds.

Application

Products | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Ischemia-Reperfusion Injury | Products > Disease Areas > Type 2 Diabetes | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Oxidative Stress and Inflammation | Products > Disease Areas > Nervous System Injury | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > HDAC

Product Information

• Catalog No.: HY-181126
• CAS No.: 1029737-28-7
• Molecular Formula: C20H20ClN3O
• Molecular Weight: 353.85
• Purity: 99.82%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source