PROTAC CDK9 degrader-12

Overview

PROTAC CDK9 degrader-12 is a selective CDK9 PROTAC degrader with a DC 50 of 23 nM. PROTAC CDK9 degrader-12 induces proteasome-dependent degradation of CDK9 , blocks CDK9-mediated HIV-1 transcriptional elongation, and reduces HIV-1 RNA synthesis. PROTAC CDK9 degrader-12 is applicable to research related to HIV-1 infection . (Pink: CDK9 ligand ( HY-181275 ); Blue: VHL ligand ( HY-120217 ); Black: linker).

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > HIV Infection | Products > Disease Areas > Sexually Transmitted Disease | Products > Disease Areas > HIV-1 Infection | Products > Disease Areas > Infection | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > CDK | Products > Signaling Pathways > HIV | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-181231
• CAS No.: 3052648-82-2
• Molecular Formula: C60H82N14O7S2
• Molecular Weight: 1175.51
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source