PF-03382792 is a potent 5-HT 4 partial agonist with a K i of 2.7 nM and an EC 50 of 0.9 nM for 5-HT 4d . PF-03382792 can penetrate the brain. PF-03382792 produces moderate increases in cortical Ach in the rat prefrontal cortex.
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