RAJQ14

Overview

RAJQ14 is a BRD4 PROTAC -like CAP-TAC ( Proteasome Cap Targeting Chimeras ) degrader. RAJQ14 binds to 19S proteasome cap subunits RPN1, RPN10, RPN13, and USP14 to recruit target proteins to the proteasome for ubiquitination-independent, proteasome-dependent degradation. RAJQ14 can be used for the research of cancer (Pink: BRD4 Ligand ( HY-181496 ); Blue: Proteasome Ligand ( HY-128978 ); Black: Linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Proteasome Cap Targeting Chimeras | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Proteasome | Products > Signaling Pathways > Epigenetic Reader Domain

Product Information

• Catalog No.: HY-181495
• CAS No.: 2375455-53-9
• Molecular Formula: C60H64Cl5N9O4S
• Molecular Weight: 1184.54
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source