SDH-IN-45 is a succinate dehydrogenase BcSDH inhibitor and mycelial growth inhibitor targeting Botrytis cinerea , with an IC 50 of 5.97 μg/mL against Botrytis cinerea . SDH-IN-45 inhibits succinate dehydrogenase , a component of the mitochondrial electron transport chain, via a unique binding mode, thereby regulating fungal energy metabolism. SDH-IN-45 causes morphological damage to Botrytis cinerea mycelia, leading to collapse and shrinkage of mycelial structures. SDH-IN-45 exhibits in vitro fungicidal activity against Botrytis cinerea . SDH-IN-45 can be used in research related to cucumber gray mold.
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