PPARδ agonist 13

Overview

PPARδ agonist 13 is a potent, selective and orally active PPARδ agonist with an EC 50 values of 0.50 nM. PPARδ agonist 13 binds to the PPARδ ligand-binding pocket and upregulates PPARδ target gene expression. PPARδ agonist 13 inhibits renal fibroblast activation, restores fatty acid oxidation, and attenuates TGF-β1-induced renal fibroblast activation. PPARδ agonist 13 exhibits anti-renal fibrosis effects in a mouse model of unilateral ureteral obstruction. PPARδ agonist 13 can be used for the research of renal fibrosis.

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Renal Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Endocrinology | Products > Signaling Pathways > PPAR

Product Information

• Catalog No.: HY-181652
• CAS No.: 3056618-93-7
• Molecular Formula: C27H24F3N2NaO4
• Molecular Weight: 520.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source