PROTAC IRAK4 degrader-14

Overview

PROTAC IRAK4 degrader-14 is an orally active IRAK4 PROTAC degrader with a DC 50 of 2.4 nM. PROTAC IRAK4 degrader-14 inhibits proinflammatory responses in multiple cell types including T cells, monocytes and keratinocytes. PROTAC IRAK4 degrader-14 is applicable to research related to psoriasis. (Pink: IRAK4 ligand ( HY-19836 ); Blue: MDM2 ligand ( HY-N0004 ); Black: linker).

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Skin Inflammation | Products > Disease Areas > Psoriasis | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > CXCR | Products > Signaling Pathways > CCR | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > IRAK | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > IFNAR

Product Information

• Catalog No.: HY-181708
• CAS No.: 3113890-51-7
• Molecular Formula: C59H68FN5O13
• Molecular Weight: 1074.20
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source