CGS 35601

Overview

CGS 35601 is the inhibitor for endothelin-converting enzyme-1 ( ECE-1 ), neutral endopeptidase 24.11 ( NEP ), and angiotensin-converting enzyme ( ACE ), with IC 50 s of 55, 2, and 22 nM, respectively. CGS 35601 suppresses the big endothelin-1 (big ET-1)- and angiotensin I-induced pressor response, and enhances circulation of atrial natriuretic peptide (ANP), regulates the cardiovascular function in SD rats.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Angiotensin-converting Enzyme (ACE)

Product Information

• Catalog No.: HY-18211
• CAS No.: 849066-09-7
• Molecular Formula: C23H31N3O4S
• Molecular Weight: 445.58
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source