Icariin

Overview

Icariin is a flavonol glycoside and a PDE5 inhibitor (IC50 = 5.9 μM) with 67-fold selectivity for PDE5 over PDE4. It exhibits antioxidant and anticancer activity. At a concentration of 1 x 107 mol/L, Icariin induces differentiation of cardiomyocytes and upregulates the expression of cardiac genes. At 20 μg/ml, Icariin increases the proliferation and differentiation of cultured human osteoblasts. Icariin affects the aging mechanism from different aspects, can delay the aging process and prevent the occurrence of senile diseases.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cardiovascular and blood system | Phosphodiesterase (PDE)

Product Information

• Catalog No.: B0084-069544
• CAS No.: 489-32-7
• Molecular Formula: C33H40O15
• Molecular Weight: 676.66
• Purity: ≥ 98%
• Storage: 2-8°C

Source

Original product source