Indotecan

Indotecan
  • CAS No.:915303-09-2
  • Grade:98.0%
  • Formula:C26H26N2O7
  • M.W.:478.49
  • Solvent:≥ 0.12 mg/mL (0.25 mM); Clear solution

Overview

Indotecan (LMP-400), an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC 50 s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Topoisomerase

Product Information

  • Catalog No.: HY-18351
  • CAS No.: 915303-09-2
  • Molecular Formula: C26H26N2O7
  • Molecular Weight: 478.49
  • Purity: 98.0%
  • Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
  • Solubility: ≥ 0.12 mg/mL (0.25 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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