Ferfluor-1 is a Ferroptosis inhibitor ( EC 50 of 57 nM in HT108 cells; EC 50 of 75 nM in OS-RC-2 cells; EC 50 of 2.3 nM in SH-SY5Y neuroblastoma cells), and ratiometric photoluminescent probe with blood-brain barrier permeability. Ferfluor-1 is a specific indicator for the fluctuation of Ferroptosis . Ferfluor-1 alleviates brain disorder diseases of in vivo stroke and PD models.
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