(±)-BI-D

Overview

(±)-BI-D is a potent ALLINI (allosteric integrase inhibitor). (±)-BI-D binds integrase at the LEDGF/p75 binding site. (±)-BI-D inhibits HIV-Luc infection in cells ( IC 50 : 0.16 μM in Psip1 knockout E9 mouse embryonic fibroblasts, 2.9 μM in wild-type E9 mouse embryonic fibroblasts).

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Infection | Products > Signaling Pathways > HIV | Products > Signaling Pathways > HIV Integrase

Product Information

• Catalog No.: HY-18601
• CAS No.: 1416258-16-6
• Molecular Formula: C25H27NO4
• Molecular Weight: 405.49
• Purity: 98.06%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.17 mM); Clear solution
• Availability: In-stock

Source

Original product source