MK-7725

Overview

MK-7725 is a selective, orally active, and blood-brain barrier-permeable agonist of the subtype 3 of the frog skin peptide receptor (BRS-3). MK-7725 has a high affinity for the human BRS-3 (hBRS-3), with an IC 50 of 3 nM, and its functional activity in the mouse-derived BRS-3 (mBRS-3) model with an EC 50 of 22 nM (105% agonistic). MK-7725 significantly reduces the body weight of obese rats and obese dogs. MK-7725 can be used for the treatment of obesity.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Bombesin Receptor

Product Information

• Catalog No.: HY-18612
• CAS No.: 1034152-93-6
• Molecular Formula: C25H19F6N5O5S
• Molecular Weight: 615.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source