LDN-57444

Overview

LDN-57444 is a reversible, competitive and site-directed inhibitor of ubiquitin C-terminal hydrolase L1 ( UCH-L1 ) , with an IC 50 of 0.88 μM and a K i of 0.40 μM; LDN-57444 also suppresses UCH-L3 activity, with an IC 50 of 25 μM.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Deubiquitinase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-18637
• CAS No.: 668467-91-2
• Molecular Formula: C17H11Cl3N2O3
• Molecular Weight: 397.64
• Purity: 99.21%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.29 mM); Clear solution
• Availability: In-stock

Source

Original product source