CYP3cide

Overview

CYP3cide (PF-4981517) is a potent, selective and time-dependent inhibitor of cytochrome P4503A4 ( CYP3A4 ) . The IC 50 values for Midazolam 1’-hydroxylase activity are 0.03 μM, 17 μM, and 71 μM for CYP3A4 , CYP3A5, and CYP3A7, respectively. CYP3cide can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on agent metabolism.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-18642
• CAS No.: 1390637-82-7
• Molecular Formula: C26H32N8
• Molecular Weight: 456.59
• Purity: 99.92%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (10.95 mM); Clear solution
• Availability: In-stock

Source

Original product source