SIBA

Overview

SIBA (5'-Isobutylthioadenosine) is a transmethylation inhibitor (SAH ( HY-19528 ) analogue), with potent anti-proliferative activity. SIBA reversibly inhibits the production of HSV-1 by blocking methylation, specifically by blocking the 5' end-capping of viral mRNA . SIBA also inhibits the growth of tumour cells in vitro and metastatic spread in vivo. SIBA can be used in cancer , HSV-1 infection and anti-malaria studies.

Application

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Product Information

• Catalog No.: HY-18684
• CAS No.: 35899-54-8
• Molecular Formula: C14H21N5O3S
• Molecular Weight: 339.41
• Purity: 99.64%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (7.37 mM); Clear solution
• Availability: In-stock

Source

Original product source