L-NAME hydrochloride

Overview

L-NAME hydrochloride inhibits NOS with an IC 50 of 70 μM. L-NAME is a precursor to NOS inhibitor L-NOARG which has an IC 50 value of 1.4 μM. L-NAME hydrochloride requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor. L-NAME hydrochloride can be used to induce hypertension and preeclampsia models.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Neurological Disease | Products > Research Areas > Infection | Products > Signaling Pathways > NO Synthase

Product Information

• Catalog No.: HY-18729A
• CAS No.: 51298-62-5
• Molecular Formula: C7H16ClN5O4
• Molecular Weight: 269.69
• Purity: 99.89%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 140 mg/mL (519.11 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source