Zorifertinib

Overview

Zorifertinib (AZD3759) is a potent, orally active, BBB-penetrant, EGFR inhibitor. At K m ATP concentrations, the IC 50 s are 0.3, 0.2, and 0.2 nM for EGFR wt , EGFR L858R , and EGFR exon 19Del , respectively. Zorifertinib induces cancer cell apoptosis . Zorifertinib has antitumor activity, and can be used for NSCLC, HCC etc. research.

Application

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Product Information

• Catalog No.: HY-18750
• CAS No.: 1626387-80-1
• Molecular Formula: C22H23ClFN5O3
• Molecular Weight: 459.90
• Purity: 99.37%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (5.44 mM); Clear solution
• Availability: In-stock

Source

Original product source