AS2444697

Overview

AS2444697 is an orally active IRAK-4 inhibitor with an IC 50 of 21 nM. AS2444697 potently inhibits human and rat IRAK-4 activity. AS2444697 exhibits renoprotective effects through anti-inflammatory action.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Arthritis | Products > Disease Areas > Rheumatoid Arthritis | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > IRAK

Product Information

• Catalog No.: HY-18992
• CAS No.: 1287665-60-4
• Molecular Formula: C19H21ClN6O4
• Molecular Weight: 432.86
• Purity: 99.54%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 1.25 mg/mL (2.89 mM); Clear solution
• Availability: In-stock

Source

Original product source