YM-16638 is an orally active leukotriene (LT) antagonist. YM-16638 can inhibit the production of LTC 4 , LTD 4 , and LTE 4 in guinea pig trachea, with IC 50 values of 0.05 μM, 0.16 μM, and 0.096 μM, respectively. YM-16638 has a dose-dependent inhibitory effect on antigen-induced early and late respiratory responses in allergic sheep.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Leukotriene Receptor
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