YM-430 is an oral active calcium entry-blocking and beta-adrenoceptor-blocking agent. YM-430 inhibits Amifampridine ( HY-14946 )-induced rhythmic contractions with an IC 50 value of 59.2 nM and inhibits arginine vasopressin-induced ST-segment depression with an IC 50 value of 36.6 mg/kg. YM-430 can be used for study of angina pectoris.
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