BW-534U87 is an orally active adenosine A1 receptor agonist and competitive adenosine deaminase ( ADA ) inhibitor ( K i =7 μM). BW-534U87 elevates brain adenosine levels and suppresses epileptiform activity. BW-534U87 demonstrate anticonvulsant efficacy in animal seizure models. BW-534U87 is promising for research of epilepsy and adenosine-related neuropsychiatric disorders.
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