rac-Olodanrigan

Overview

rac-Olodanrigan (rac-EMA401; EMA400) is a racemic mixture of the S-enantiomer (EMA401; HY-13106) and R-enantiomer (EMA402). rac-Olodanrigan is a potent and selective AT 2 receptor antagonist with IC 50 s of 75.2 nM and 2918 nM for AT 2 R and AT 1 R, respectively. rac-Olodanrigan evokes dose-dependent relief of mechanical allodynia in the ipsilateral hind paws of rats with a chronic constriction injury (CCI) of the sciatic nerve.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Angiotensin Receptor

Product Information

• Catalog No.: HY-19202
• CAS No.: 152362-51-1
• Molecular Formula: C32H29NO5
• Molecular Weight: 507.58
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source