CGP-49823

Overview

CGP-49823 is an orally active and highly selective antagonist of the neurokinin 1 receptor ( NK1 receptor ). CGP-49823‘s potency is significantly higher in isolated spinal cords of hamsters than in those of rats. CGP 49823 exhibits a significant anti-anxiety effect in social interaction experiments of rats, and its tolerance develops slowly, without causing anxiety-like withdrawal reactions after discontinuation. CGP-49823 can be used in anxiety and depression research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Neurokinin Receptor

Product Information

• Catalog No.: HY-19203
• CAS No.: 150705-88-7
• Molecular Formula: C31H33N3O
• Molecular Weight: 463.61
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source