Azvudine

Overview

Azvudine (RO-0622) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV , HBV and HCV . Azvudine exerts highly potent inhibition on HIV-1 (EC 50 s ranging from 0.03 to 6.92 nM) and HIV-2 (EC 50 s ranging from 0.018 to 0.025 nM). Azvudine inhibits NRTI-resistant viral strains. Azvudine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Application

Products | Products > Disease Areas > Hepatitis C Virus Infection | Products > Disease Areas > Infection | Products > Disease Areas > Hepatitis Virus Infection | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Reverse Transcriptase | Products > Signaling Pathways > HIV | Products > Signaling Pathways > HBV | Products > Signaling Pathways > HCV

Product Information

• Catalog No.: HY-19314
• CAS No.: 1011529-10-4
• Molecular Formula: C9H11FN6O4
• Molecular Weight: 286.22
• Purity: 99.38%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (8.73 mM); Clear solution
• Availability: In-stock

Source

Original product source