Lifitegrast-d 6

Overview

Lifitegrast-d 6 (SAR 1118-d 6 ) is deuterium labeled Lifitegrast. Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC 50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Others | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Isotope-Labeled Compounds

Product Information

• Catalog No.: HY-19344S1
• CAS No.: 2249814-79-5
• Molecular Formula: C29H18D6Cl2N2O7S
• Molecular Weight: 621.52
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source