DC260126

Overview

DC260126 is a potent antagonist of GPR40 (FFAR1) . DC260126 dose-dependently inhibits GPR40-mediated Ca 2+ elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC 50 : 6.28, 5.96, 7.07, 4.58 μM, respectively). DC260126 could protect MIN6 β cells from palmitate-induced ER stress and apoptosis .

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Free Fatty Acid Receptor | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-101906
• CAS No.: 346692-04-4
• Molecular Formula: C16H18FNO2S
• Molecular Weight: 307.38
• Purity: 99.57%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (8.13 mM); Clear solution
• Availability: In-stock

Source

Original product source