Latanoprost ene bunod (NCX116; LBN) (Standard) is the analytical standard of Latanoprost ene bunod. This product is intended for research and analytical applications. Latanoprost ene bunod is a nitric oxide-releasing prostaglandin F 2 α analog. Latanoprost ene bunod is a prodrug that, upon instillation into the eye, is hydrolyzed by corneal esterases into two active metabolites: Latanoprost ( HY-B0577 ) and NO. Latanoprost activates the prostaglandin FP receptor to increase the outflow of aqueous humor through the uveoscleral pathway. NO increases aqueous humor drainage through the trabecular meshwork pathway, achieving synergistic enhancement targeting the dual pathways of aqueous humor outflow. Latanoprost ene bunod can be used in research related to open-angle glaucoma and ocular hypertension.
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