Seladelpar (MBX-8025) lysine is an orally active, potent and specific PPARδ agonist with an EC 50 of 2 nM. Seladelpar lysine shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar lysine can be used for the study of primary biliary cholangitis.
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