Naldemedine

Overview

Naldemedine (S-297995) is an orally active μ-opioid receptor antagonist (PAMORA). Naldemedine shows potent binding affinities ( Ki =0.34, 0.43, 0.94 nM, respectively) and antagonist activities ( IC 50 =25.57, 7.09, 16.1 nM, respectively) for recombinant human μ-, δ-, and κ- opioid receptors. Naldemedine can be used in opioid-induced constipation (OIC) research. Naldemedine is predicted to bind to 3CL pro encoded by SARS-CoV2 genome.

Application

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Product Information

• Catalog No.: HY-19627
• CAS No.: 916072-89-4
• Molecular Formula: C32H34N4O6
• Molecular Weight: 570.64
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source