Ilginatinib hydrochloride

Overview

Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable JAK2 inhibitor, with an IC 50 of 0.72 nM, 46-, 54-, and 31-fold selectivity for JAK2 over JAK1 ( IC 50 , 33 nM), JAK3 ( IC 50 , 39 nM), and Tyk2 ( IC 50 , 22 nM).

Application

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Product Information

• Catalog No.: HY-19631B
• CAS No.: 1239358-85-0
• Molecular Formula: C21H21ClFN7
• Molecular Weight: 425.89
• Purity: 98.92%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (5.87 mM); Clear solution
• Availability: In-stock

Source

Original product source