Pranidipine

Overview

Pranidipine (OPC-13340) is an orally active L-type voltage-dependent calcium channel ( L-VDCC ) blocker with a K i value of 0.16 nM. Pranidipine inhibits calcium-induced contraction, suppresses slow-response action potentials, shortens action potential duration, reduces systolic and diastolic blood pressure, and exerts vasodilatory effects. Pranidipine enhances its vasodilatory effect by blocking NO decomposition. Pranidipine can be used in research related to essential hypertension, angina pectoris, myocardial infarction, and dilated cardiomyopathy.

Application

Products | Products > Disease Areas > Hypertension | Products > Disease Areas > Angina | Products > Disease Areas > Myocardial Infarction | Products > Disease Areas > Cardiomyopathy | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Heart Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > NO Synthase

Product Information

• Catalog No.: HY-19664
• CAS No.: 99522-79-9
• Molecular Formula: C25H24N2O6
• Molecular Weight: 448.47
• Purity: 99.52%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.25 mg/mL (5.02 mM); Clear solution
• Availability: In-stock

Source

Original product source