Tauroursodeoxycholate dihydrate

Overview

Tauroursodeoxycholate dehydrate is an orally active taurine conjugate of Ursodeoxycholic acid ( HY-13771 ). Tauroursodeoxycholate dehydrate inhibits caspase-3/7 , Apoptosis , IRE1α/TRAF2/NF-κB , prevents JNK phosphorylation, inhibits ROS generation, and activates Akt signaling. Tauroursodeoxycholate dehydrate prevents cataract formation, reduces renal tubular damage in type 2 diabetic mice, reduces I/R injury in liver, and inhibits intestinal inflammation and barrier disruption in nonalcoholic fatty liver disease.

Application

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Product Information

• Catalog No.: HY-19696B
• CAS No.: 117609-50-4
• Molecular Formula: C26H49NO8S
• Molecular Weight: 535.73
• Purity: 99.96%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (3.88 mM); Clear solution
• Availability: In-stock

Source

Original product source