TBA-7371

Overview

TBA-7371 is an orally active and non-covalent inhibitor of Decaprenylphosphoryl-β-D-ribose oxidase ( DprE1 ) of Mycobacterium tuberculosis (MIC=0.64 μg/mL). TBA-7371 can block the synthesis of arabinose in the bacterial cell wall, resulting in cell wall structural defects, thereby exerting an anti-tuberculosis effect. TBA-7371 can be used in the research of anti-tuberculosis drugs and has a synergistic bactericidal effect with Bedaquiline ( HY-14881 ) and other drugs.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Mycobacterium Tuberculosis Infection | Products > Disease Areas > Lung Fibrosis | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-19750
• CAS No.: 1494675-86-3
• Molecular Formula: C18H21N5O3
• Molecular Weight: 355.39
• Purity: 99.61%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Availability: In-stock

Source

Original product source